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Association of ABCB1, 5-HT3B receptor and CYP2D6 genetic polymorphisms with ondansetron and metoclopramide antiemetic response in Indonesian cancer patients treated with highly emetogenic chemotherapy.

Perwitasari, Dyah A and Wessels, Judith A M and van der Straaten, Robert J H M and Baak-Pablo, Renee F and Mustofa, Mustofa and Hakimi, Mohammad and Nortier, Johann W R and Gelderblom, Hans and Guchelaar, Henk-Jan (2011) Association of ABCB1, 5-HT3B receptor and CYP2D6 genetic polymorphisms with ondansetron and metoclopramide antiemetic response in Indonesian cancer patients treated with highly emetogenic chemotherapy. Japanese journal of clinical oncology, 41 (10). pp. 1168-76. ISSN 1465-3621

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Abstract

Our study shows that in Indonesian cancer patients treated with highly cytostatic emetogenic, carriership of the CTG haplotype of the ABCB1 gene is related to an increased risk of delayed chemotherapy-induced nausea and vomiting.

Item Type: Article
Subjects: R Medicine > R Medicine (General)
Depositing User: dyah aryani
Date Deposited: 31 Jul 2012 22:33
Last Modified: 31 Jul 2012 22:33
URI: http://eprints.uad.ac.id/id/eprint/1467

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