MONITORING OF ANTITHROMBOTICS’ADVERSE EFFECT ON UNSTABLE ANGINA PECTORIS PATIENTS IN A PUBLIC HOSPITAL OF YOGYAKARTA, INDONESIA

Perwitasari, Dyah Aryani (2009) MONITORING OF ANTITHROMBOTICS’ADVERSE EFFECT ON UNSTABLE ANGINA PECTORIS PATIENTS IN A PUBLIC HOSPITAL OF YOGYAKARTA, INDONESIA. International Journal of Current Pharmaceutical Research, 1 (1). pp. 61-66. ISSN 0975-7066

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Abstract

Patients with unstable angina pectoris are at risk of death or recurrent ischemic events, despite receiving aspirin and heparin. The benefit from using aspirin in high‐risk vascular disease patients comes at the cost of increased gastrointestinal complications. The complications include gastroduodenum ulcerations, dyspepsia, esophagitis and ulcerations in the stomach and duodenum. This research investigated the monitoring of antithrombotics adverse effect in a public hospital of Yogyakarta during January 2006‐December 2007.
This research used patients’medical records as patients’database in adverse drug effect monitoring. The
populations were all unstable angina inpatients in a public hospital of Yogyakarta January 2006 to December 2007.
We identified that the adverse effects’ monitoring has been done well. The monitoring has been done to the gastrointestinal distrubance (100%), bleeding risk (30%), thrombocytopenia (35%) and renal dysfunction (20%). There were 35% patients experienced antithrombotics’adverse effects, such as bleeding, thrombocytopenia and renal dysfunction. Clinical manifestation of dual antithrombotic therapy was experienced by 10% patients.

Item Type: Artikel Umum
Subjects: R Medicine > R Medicine (General)
Depositing User: dyah aryani
Date Deposited: 31 Jul 2012 22:33
Last Modified: 31 Jul 2012 22:33
URI: http://eprints.uad.ac.id/id/eprint/1475

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