Syahrana, Nur Azizah and Akrom, Akrom and Darmawan, Endang Similarity Check: Efek Serbuk Bunga Rosella Merah (Hibiscus sabdariffa L.) terhadap Ekspresi IL-10 pada Sukarelawan Sehat. Jurnal Farmasi Dan Ilmu Kefarmasian Indonesia.
Preview |
Text
Efek_Serbuk_Bunga_Rosella_Merah__Hibiscus_sabdarif.pdf Download (1MB) | Preview |
Abstract
Background: Rosella calyx (Hibiscus sabdariffa L.) contain phenol and anthocyanin flavonoids that have activity as antioxidants and can stimulate the immune system. Objective: The purpose of this study was to investigate the effect of rosella powder capsule on expression IL-10 using pre and post test method on 21 healthy volunteers who fulfilled inclusion criteria and willing to fill informed consent. Methods: Volunteers were given rosella powder in capsules form with 500 mg dose for 30 days and IL-10 was examined using flowsitometric method on days 0.30 and 45. The results were analyzed using SPSS with wilcoxon test. Results: The value of IL10 expression in the 0.30 and 45 day volunteers were 0.42 ± 0.24; 0.83 ± 0.47 and 1.06 ± 0.67. These results showed that IL-10 expression had an effect on day 0 to 30 (p < 0.05) and IL-10 expression did not affect the 30 day of the 45 (p > 0.05). Conclusion: administration of rosella powder capsules (Hibiscus sabdariffa L.) dose 500 mg/day for 30 days increased the expression of IL-10, but within normal limits on healthy volunteers.
Keywords: roselle, IL-10 expression, healthy volunteers
| Item Type: | Other |
|---|---|
| Subjects: | Z Bibliography. Library Science. Information Resources > ZA Information resources > ZA4050 Electronic information resources |
| Divisi / Prodi: | Faculty of Pharmacy (Fakultas Farmasi) > Program of Professional Pharmacist |
| Depositing User: | Dr.rer.nat Endang Darmawan |
| Date Deposited: | 13 May 2020 14:58 |
| Last Modified: | 13 May 2020 14:58 |
| URI: | http://eprints.uad.ac.id/id/eprint/18668 |
Actions (login required)
 |
View Item |