Anti-inflammatory effects of avocado peels against inflammation induced by carrageenan in mice

Aprilianto, Eko and Swantika Yuan, Alexander Vito Harmoni and Pradita, Claudia Darantika and Hendra, Phebe (2019) Anti-inflammatory effects of avocado peels against inflammation induced by carrageenan in mice. Pharmaciana, 9 (2). pp. 219-226.

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Abstract

The aim of this research is to investigate the anti-inflammatory activity of avocado peel against carrageenan-induced inflammation in mice. The group of mice that was used as a negative control group to test the anti-inflammatory activity of infusion and decoction (group I) were given aquadest, while the group for testing the activity of extract (group II) was given CMC-Na. The positive control group (group III) was given potassium diclofenac. Groups IV-VI were given avocado peel infusion with the following doses 667.5; 1335; and 2670 mg/kgBW respectively. Groups VII-IX were given avocado peel decoction with the same doses as the previous groups. Groups X-XII were given 830; 1670; and 3330 mg/kgBW of avocado peel extract respectively. The paw edema were measured using a digital caliper for 6 hours afterwards after carrageenan injection. There were a significant (p<0.05) reduction in paw edema at all doses of infusion, decoction, and extract of avocado peel. Based on the research, it can be concluded that the avocado peels have anti-inflammatory activities.

Item Type: Artikel Umum
Subjects: R Medicine > RS Pharmacy and materia medica
Divisi / Prodi: Faculty of Pharmacy (Fakultas Farmasi) > S1-Pharmacy (S1-Farmasi)
Depositing User: jurnal pharmaciana
Date Deposited: 29 Sep 2021 21:23
Last Modified: 29 Sep 2021 21:23
URI: http://eprints.uad.ac.id/id/eprint/28775

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