Susanti, Hari and Wahyuono, Subagus and Sari, Ika Puspita and Susidarti, Ratna Asmah (2018) Peer Review Antihypercholesterol Activity of Costus Speciosus Water Extract. [Artikel Dosen]
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Abstract
Introduction: Hypercholesterolemia is one of the causes of cardiovascular disease. Costus
speciosus (CS) is known empirically as an antihypercholesterol remedy. Material and Method:
This study was conducted to determine the effect of water extract of CS on cholesterol blood
serum level of rat induced-propylthiouracil (PTU). The antihypercholesterol activity performed
on male Wistar rats which induced 0.01% PTU (mixed in drinking water, 14 day-induction)
was followed by the administration of CS for 14 days. The animals were randomly divided into
seven groups: Solvent control (carboxylmethylcellulose 0.5% w/v in water), positive control
(simvastatin at dose 7.2 mg/kg BW), negative control (water), CS extract 50, 100, and 200 mg/kg,
and normal control. The cholesterol levels were measured at day 0th, 14th, and 28th. Result
and Conclusion: Results showed that administration of
| Item Type: | Artikel Dosen |
|---|---|
| Subjects: | Q Science > Q Science (General) R Medicine > R Medicine (General) R Medicine > RS Pharmacy and materia medica |
| Divisi / Prodi: | Faculty of Pharmacy (Fakultas Farmasi) > Program of Professional Pharmacist |
| Depositing User: | Mrs Hari Susanti |
| Date Deposited: | 20 May 2022 03:01 |
| Last Modified: | 20 May 2022 03:01 |
| URI: | http://eprints.uad.ac.id/id/eprint/35012 |
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