Bukti korespondensi JFSK 2022 : ANTIBACTERIAL ACTIVITY OF Parsea americana mill. PEELS EXTRACTAND FRACTION CONTAINING PHENOLIC COMPOUND AGAINSTStaphylococcus aureus

Sulistyani, Nanik (2022) Bukti korespondensi JFSK 2022 : ANTIBACTERIAL ACTIVITY OF Parsea americana mill. PEELS EXTRACTAND FRACTION CONTAINING PHENOLIC COMPOUND AGAINSTStaphylococcus aureus. [Artikel Dosen]

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Abstract

Parsea americana mill. is a natural resource that has been studied as anantibacterial agent. The pulp, peel, and seed of Parsea americana mill. have potential
as an antibacterial agent. This research aims to determine the antibacterial activityand phenolic content of Parsea americana mill. peels extract and fraction against
Staphylococcus aureus. Parsea americana mill. was macerated with 96%ethanol andthen fractionated with solvents of dif erent level of polarity such as n-hexane, ethyl
acetate, and methanol solvent, respectively. Antibacterial activity was tested by theKirby-Bauer method to determine the most active fraction in inhibiting the growthof
Staphylococcus aureus. Total phenolics content in the extract and fractions weremeasured spectrometrically according to the Folin-Ciocalteu method and calculatedas gallic acid equivalents (GAE). Antibacterial activity test of the 96%ethanol extract, ethyl acetate fractions, and methanol fractions at a concentration of 10%w/v was
showed inhibition zone diameter. At the same time, the n-hexane fraction showednoinhibition zone diameter. The highest inhibition zone is an ethyl acetate fractionas
8.33 ± 0.577 mm. Ethyl acetate fraction of Parsea americana mill. resulted intheamount of 536.26 ± 14.29 mg GAE/g fraction measured by the Folin-Ciocalteureagent method. The conclusion is that ethyl acetate fraction is the most active ininhibiting the growth of Staphylococcus aureus and has then the highest phenoliccontent.

Item Type:	Artikel Dosen
Subjects:	A General Works > AC Collections. Series. Collected works
Divisi / Prodi:	Faculty of Pharmacy (Fakultas Farmasi) > Pharmacy Doc
Depositing User:	Dr Nanik Sulistyani
Date Deposited:	14 Nov 2022 04:51
Last Modified:	14 Nov 2022 04:51
URI:	http://eprints.uad.ac.id/id/eprint/37503

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