Hasil cek similarity" Quality of Life of Cancer Patients during Chemotherapy in Indonesia: A Comparison of EORTC QLQ-C30 and EQ-5D-5L, Based on Patients’ Characteristics

Perwitasari, Dyah Aryani and Purba, Fredrick D. and Candradewi, Susan F. and Dania, Haafzah and Irham, Lalu Muhammad and Faridah, Imaniar Noor and Septiantoro, Bayu P. (2022) Hasil cek similarity" Quality of Life of Cancer Patients during Chemotherapy in Indonesia: A Comparison of EORTC QLQ-C30 and EQ-5D-5L, Based on Patients’ Characteristics. International Journal of Clinical Practice.

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Abstract

One of the important outcomes to defne the success of cancer treatment is the health-related quality of life (HRQoL) that can be
measured using generic and/or specifc instruments. Our study aims to defne the cancer patients’ HRQoL in some hospitals in
Indonesia as measured by the European Organization for Research and Treatment for Cancer (EORTC QLQ-C30) and the EQ5D-5L, to defne the diferences of cancer patients’ HRQoL referring to patients’ characteristics, and to explore determinants of
cancer patients’ HRQoL. We recruited 451 cancer patients using a cross-sectional design in two referral hospitals in Central Java,
Indonesia, using the purposive sampling technique. All subjects, recruited from July 2020 to October 2021, met the inclusion
criteria, namely, adult patients diagnosed with cancers in all stages who willingly participated in the study. Te Indonesian value
set was used to obtain the EQ-5D-5L index score. We further analyzed the data based on cancer stages and compared two
questionnaires using independent t test. We highlighted that most of the cancer patients are female (69.4%), young (86%), and at
advanced stages of cancer (54.1%). Te physical and role functions and global health status of the cancer patients are poor, and the
most severe symptom is fatigue. Moreover, most of them experience severe pain and perform daily activities with difculties. Some
patients’ characteristics show signifcant infuences on the HRQoL domains in both questionnaires (p < 0.05). Interestingly, both
of the questionnaires have shown signifcant correlations between similar domains and revealed the poor HRQoL of advanced
cancer patients (p < 0.05). Our study fnds that cancer patients still have poor HRQoL in some domains. We suggest to the health
providers that they apply education and psychological intervention to increase their HRQoL.

Item Type:	Artikel Umum
Subjects:	R Medicine > RM Therapeutics. Pharmacology
Divisi / Prodi:	Faculty of Pharmacy (Fakultas Farmasi) > S2-Master of Pharmacy (S2-Farmasi)
Depositing User:	Lalu Muhammad Irham, M.Farm., Ph.D
Date Deposited:	06 Mar 2023 02:49
Last Modified:	06 Mar 2023 02:49
URI:	http://eprints.uad.ac.id/id/eprint/40524

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