Comparison of small molecules VEGFR inhibitors in the treatment of renal cell carcinoma

Tan, Jie Yi and Jaipuria, Aadya and Priefer, Ronny (2023) Comparison of small molecules VEGFR inhibitors in the treatment of renal cell carcinoma. Pharmaciana, 13 (2). pp. 211-223. ISSN ISSN:2088-4559,e-ISSN:2477-0256

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Abstract

Vascular endothelial growth factors receptors (VEGFR) inhibitors play a vital role in the treatment of renal cell carcinoma. These are small molecules that predominantly exhibit anti-angiogenesis activity in conjunction with other anti-tumor effects. These drug therapies are approved for the use in patients as frontline agents or adjuvant therapy in renal cell carcinoma. However, VEGFR inhibitors are associated with undesirable adverse events, with some having a more manageable toxicity profile compared to others. As a result, choice of treatment poses a challenge for healthcare providers and patients. Nonetheless, these agents demonstrate improved disease/progression free survival (DFS/PFS) values and remain a critical component in the treatment of kidney cancer.

Item Type:	Artikel Umum
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisi / Prodi:	Faculty of Pharmacy (Fakultas Farmasi) > S1-Pharmacy (S1-Farmasi)
Depositing User:	jurnal pharmaciana
Date Deposited:	19 Aug 2023 03:49
Last Modified:	19 Aug 2023 04:28
URI:	http://eprints.uad.ac.id/id/eprint/46432

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