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PENGARUH PEMBERIAN EKSTRAK ETANOL FIERBA MENIRAN (Phylanthus nirurri)TERHADAP AKTIVITAS FAGOSITOSIS MAKROFAG MENCIT Swiss YANG DIINFEKSI Plasmodium berghei

Akrom, Akrom and Mustofa, Mustofa and Indwiani, astuti (2005) PENGARUH PEMBERIAN EKSTRAK ETANOL FIERBA MENIRAN (Phylanthus nirurri)TERHADAP AKTIVITAS FAGOSITOSIS MAKROFAG MENCIT Swiss YANG DIINFEKSI Plasmodium berghei. Sains Kesehatan, VoL 18 (no 3). pp. 411-425. ISSN 1411-6197

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Abstract

This studies was carried out to evaluate the influence of ethanoi extract offlrullantlrus niruri (EEPN) to the macrophage phagocytosis activity of male Swiss mice during P.berghei infection.The laboratory experimental research conducted on 75 male Swiss mice divided in five group. The group one to three as experimental group were ingested EEPN 5,10 and 100 mg/kgBW/ day respeclively. The group four as positive control group is ingested malaria vaccine P.berghei on erithrocyie stadium and the group five as negative control group is ingested water. The EEPN, malaria vaccine'and water is ingested during fourteen day. On the fourteenth day each group was infected by P. berghei. The phagocyiosis activity of macrdphage response was observed. The macrophage phagocytosis activity response was evaluated with latex test. The data was processed with SPSS program; the average differences between groups were analyzed by anova. the result showed that Swiss mice infected bv P. berghei with EEPN 10 mg/kgBW/day group increase the macrophage phagorytosis activity better than EEPN 100 mg/kgBW/day. The immunostimulant effect of P. niruri ethanol extract is temporary.

Item Type: Artikel(umum)
Subjects: R Medicine > RS Pharmacy and materia medica
Depositing User: Akrom
Date Deposited: 15 Mar 2018 03:23
Last Modified: 15 Mar 2018 03:23
URI: http://eprints.uad.ac.id/id/eprint/9535

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