Physical Properties and Irritation Degree of Green Tea (Camellia sintesis L) extract Cream with Variations Concentration of Vitamin C as Antioxidants

Sugihartini, Nining and Alimsyah, F and Zaenab, Zaenab and Susanti, Hari (2014) Physical Properties and Irritation Degree of Green Tea (Camellia sintesis L) extract Cream with Variations Concentration of Vitamin C as Antioxidants. Proceding, International Conference on Restorative Justice. ISSN ISBN : 978-979-18458-7-8

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Abstract

Epigallocatechin gallate (EGCG) is a polyphenol as the active compound that naturally found in many plants of tea (Camellia sinensis). That is effective as an anti-inflamation so it needs to be made into cream dosage form. One of the factors that must be considered in the development of a green tea extract cream formulations iss physical properties of EGCG that is easily oxidate so it needs to be added antioxidant. One of the widely used antioxidant is vitamin C. The purpose of this study was to determine the effect of variations concentration of vitamin C as antioxidants toword the physical properties and irritation degree of green tea extract cream.
The cream used in the study contained 0.2% greeen tea extract and variations concentration of vitamin C as antioxidants at 1%, 5% and 10%. All of cream are toward physical and iritation degree on guinea pigs. The data of physical properties and irritation degree of cream are analysed by parametric test of one way ANOVA with 90% of confidence level.
The results showed that increasing concentration of Vitamin C Will make decrease PH, spreading value and irritation degree but increasee the contact adhesion of cream.
The conclusion of this indicate that 10% of vitamin C as antioxidants is the best concentration to obtain the best physical properties with minimun irritation degree of greem tea extract cream.

keyword : green tea,cream, anti oxidants, irritation degree.

Item Type:	Artikel Umum
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisi / Prodi:	Faculty of Pharmacy (Fakultas Farmasi) > S2-Master of Pharmacy (S2-Farmasi)
Depositing User:	Nining Sugihartini
Date Deposited:	27 Mar 2018 05:12
Last Modified:	27 Mar 2018 05:12
URI:	http://eprints.uad.ac.id/id/eprint/9717

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