Pengaruh Pemberian Produk "X" yang Mengandung Ekstrak Daun Murbei (Morus alba L.) terhadap Kadar Trigliserida pada Tikus Jantan Galur Wistar

Arief, Ferry and Sofia, Vivi (2013) Pengaruh Pemberian Produk "X" yang Mengandung Ekstrak Daun Murbei (Morus alba L.) terhadap Kadar Trigliserida pada Tikus Jantan Galur Wistar. FARMASAINS, 2 (2). pp. 82-85. ISSN 2086-6968

Text Pengaruh_Pemberian_Produk_X_yang_Mengandung_Ekstrak_Daun_Murbei_(Morus alba L.)_terhadap_Kadar_Trigliserida_pada_Tikus_Jantan_Galur_Wistar.pdf Download (1MB)

Abstract

Mulberry (Morus alba L.) is one of the source of a herbal medicine. The leaf has benn reported as could reduces triglycerides level. Quercetin in mulberry leaves inducec triglycerides catabolism to fatty acid and glycerol and induces fatty acid oxidation ro energy. The aim of this srudy is to know effect of product “X” which contained mulberry leaves extract on the triglycerides of male Wistar rats. This study used 25 laboratory male Wistar rats, od 2-3 months age and 150-200 grams in body weight. Twenty five rats were a divided into five groups at randomly: group A as the solvent control group. Group B as negative control group was fed a high-fat diet, group C as the solvent control group was given 0,5% CMC-Na, group D as the positive control was given gemfibrozilm126 mg/kgBW, and group E was given “X” product 630 mg/KgBW. Each group, which orally were fed the treadment for 7 days. The triglycerides level was checked on day 8 used an easy touch. The data of triglycerides level was obtained and analyzed statistically by ANOVA test with a confidence level 95%. The result showed, that the group that given “X” product at a dose of triglycerides level 9,45% (p<0,05) and 24,78% (p<0,05). As conclution the “X” products at a dose of 630 mg/KgBW can decrease triglycerides level in male Wistar rats, but not as big as gemfibrozile effect.
Keywords: Mulberry leaves, Triglycerides, gemfibrozile

Item Type:	Artikel Umum
Subjects:	R Medicine > R Medicine (General)
Divisi / Prodi:	Faculty of Pharmacy (Fakultas Farmasi) > Pharmacy Doc
Depositing User:	Vivi Sofia
Date Deposited:	18 Dec 2018 01:56
Last Modified:	18 Dec 2018 01:56
URI:	http://eprints.uad.ac.id/id/eprint/11887

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