Widyaningsih, Wahyu and Salamah, Nina and Qulsum Maulida, Fella (2016) Hasil Pree Review Teman Sejawat The effects of ethanolic extract of green algae (ulva lactuca l.) on blood cholesterol levels in male rats induced by a high fat diet. Indonesian Journal of Medicine and Health Faculty of Medicine Universitas Islam Indonesia, Yogyakarta.
Preview |
Text
Review the effects of ethanolic.pdf Download (1MB) | Preview |
Abstract
Background: Nowadays, cardiovascular disease is increasing in number
each year. It is triggered by high cholesterol diet consumed by urban
people. Green algae (Ulva lactuca L.) contains phytomelatonin levels that
can ease cholesterol.
Objective: To know about the effect of giving green algae ethanolic extract
in male strain Wistar mice’s cholesterol level.
Methods: This research involved 36 male strain Wistar mice divided to
six groups. Negative control injected with 2 ml/200 gBW lard, positive
control injected with 0,18 mg/200 gBW simvastatin and lard, group III, IV,
V each given lard and injected with ethanolic extract of green algae at a
dose of 50 mg/kgBW, 100 mg/kgBW and 200 mg/kgBW respectively, and
normal control given AD 2 dietary treatment. Each group was given the
same treatment peroral in 56 days and the blood was taken every 14 days
through sinus orbitalis. The blood cholesterol level was analyzed by using
enzymatic CHOD-PAP method. Data obtained were statistically examined
using Two way ANOVA , Kolmogorov Smirnov, Levene’s method and LSD
with confidence level at 95%.
Results: The blood cholesterol level were not significanly different
between the negative and normal control. The result of cholesterol level
for 14, 28, and 42 days for all group did not increase compared to negative
control, but cholesterol level in group with 200 mg/kgBW dose extract
indicated significant difference with negative control for 56 day.
Conclusion: Giving ethanolic extract of green algae for 56 days decreased
blood cholesterol level in male rats.
| Item Type: | Other |
|---|---|
| Keyword: | reen algae, Ulva lactuca L., cholesterol,lard |
| Subjects: | R Medicine > RS Pharmacy and materia medica |
| Divisi / Prodi: | Faculty of Pharmacy (Fakultas Farmasi) > S1-Pharmacy (S1-Farmasi) |
| Depositing User: | Ms Nina Salamah |
| Date Deposited: | 29 Jun 2018 02:33 |
| Last Modified: | 05 Jul 2018 01:15 |
| URI: | http://eprints.uad.ac.id/id/eprint/10528 |
Actions (login required)
 |
View Item |