Anti-Inflammatory Activity of Cream Type O/W with Concentration Variation of Essential Oils of Clove (Syzigium aromaticum)

Sugihartini, Nining and Haque, Aina Fatkhil and Yuwono, Tedjo (2017) Anti-Inflammatory Activity of Cream Type O/W with Concentration Variation of Essential Oils of Clove (Syzigium aromaticum). Advanced Science Letters, 23 (12). pp. 12514-12517. ISSN 19366612, 19367317

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Abstract

Clove essential oil (Syzigium aromaticum) has been proven as anti-inflammatory agent. Formulation in the
cream type O/W preparations was required to be utilized by the community. The aims of this research was to
determined activity of cream as anti-inflammatory with concentration variation of essential oil. Cream was made
by melting method with concentration variation of clove essential oil: 2.5%; 5%; 10%. The cream was evaluated
for anti-inflammatory activities by using animal test BALB/c strain of mice that previously has been induced
inflammation with crotton oil. The results showed that increasing concentrations of clove essential oils tended
to increase the thickness of skin folds, thickness of the epidermis, the number of inflammatory cells and the
number of cells with COX-2 expression. The optimal concentration of essential oils in cream type O/W as
anti-inflammatory was 2.5%.
Keywords: Clove Essential Oil, Cream Type O/W, Anti-Inflammatory.

Item Type:	Artikel Umum
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisi / Prodi:	Faculty of Pharmacy (Fakultas Farmasi) > S2-Master of Pharmacy (S2-Farmasi)
Depositing User:	Nining Sugihartini
Date Deposited:	10 Jul 2019 05:15
Last Modified:	10 Jul 2019 05:15
URI:	http://eprints.uad.ac.id/id/eprint/14080

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