Improved hypoglycemic effect of anthocyanin extract combination from red rice and black soybean

Rahayu, Wahidah Mahanani and Astuti, Mary and Marsono, Yustinus (2019) Improved hypoglycemic effect of anthocyanin extract combination from red rice and black soybean. In: international conference On Advanced Molecular Bioscience and Biomedical Engineering, Malang.

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Abstract

Abstract. Red rice and black soybean, both contains anthocyanin, have long been part of
diabetic patient diet. was investigated. This study aimed to investigate possible synergetic antihyperglycemic
effect of crude anthocyanin extract from red rice and black soybean
combination. Observation was conducted on glucose level, total plasma antioxidant capacity,
and antioxidant enzyme superoxide dismutase (SOD) activity of STZ-NA induced
hyperglycemic 2-months old male Sprague Dawley rats. Thirty rats were divided into five
groups (n=6] of healthy group, hyperglycemic control, and three hyperglycemic treated groups.
Treated groups were orally administered with daily dose of 100 mg/kg body weight of
anthocyanin extract from red rice, black soybean, and their 1:1 (w/w) combination for 35 days.
Anthocyanin extract consumption significantly reduced blood glucose by 45.3%-50.9%,
prevented body weight loss by 36.42-51.52%, increased total antioxidant capacity by 15.84 –
25.30% and SOD activity than those of hyperglycemic groups. Consumption of anthocyanin
from red rice and black soybean significantly improve hyperglycemic rats condition. Possible
synergetic effect of extract combination was indicated by 8.2 % lower plasma glucose
reduction and 40.06% higher SOD activity than those of each material effect.

Item Type:	Conference or Workshop Item (Paper)
Subjects:	Q Science > Q Science (General)
Divisi / Prodi:	Faculty of Industrial Technology (Fakultas Teknologi Industri) > S1-Food Technology (S1-Teknologi Pangan)
Depositing User:	S.TP.,M.Sc WAHIDAH MAHANANI RAHAYU
Date Deposited:	17 Feb 2022 01:39
Last Modified:	17 Feb 2022 01:39
URI:	http://eprints.uad.ac.id/id/eprint/32594

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