Hasil cek similarity"Artikel: The Role of Bamboo Shoot Gigantochloa Apus Extract in Decreasing the IL-17/IL-10 Ratio Level in the Atherosclerosis Process"

Soesanto, Edy and Pranata, Satriya and Rejeki, Sri and Irham, Lalu Muhammad (2021) Hasil cek similarity"Artikel: The Role of Bamboo Shoot Gigantochloa Apus Extract in Decreasing the IL-17/IL-10 Ratio Level in the Atherosclerosis Process". Open Access Macedonian Journal of Medical Sciences, 9 (A). ISSN 1857-9655

[thumbnail of HASIL CEK_The Role of Bamboo Shoot Gigantochloa Apus Extract in Decreasing the IL-17_IL-10 Ratio Level in the Atherosclerosis Process (1).pdf]

Text
HASIL CEK_The Role of Bamboo Shoot Gigantochloa Apus Extract in Decreasing the IL-17_IL-10 Ratio Level in the Atherosclerosis Process (1).pdf
Download (1MB)

Official URL: https://oamjms.eu/index.php/mjms/article/view/6675

Abstract

BACKGROUND: Atherosclerosis begins with injury to the endothelial, progressive, and increases by 3% per year since the age of a person passes 20 years. The ratio of the number of pro and anti-inflammatory cytokines can describe the development of the process of atherosclerosis so that the higher the ratio will increase the chance of atherosclerosis.

AIM: The purpose of this study was to examine the effect of Bamboo shoot Gigantochloa apus (BSGA) extract on decreasing interleukin-17 (IL-17)/IL-10 level ratios in New Zealand White rabbits given an atherogenic diet.

METHODS: This study uses BSGA extract freeze-dried aged 1–2 weeks and New Zealand White rabbits. Atherogenic feed uses 0.5% egg yolk and 5% pork oil which is added to the standard feed. Randomized pre- and post-test with control group design by dividing into four groups were used in this study.

RESULTS: The mean ratio of IL-17 levels with IL-10 between before and after (p < 0.005) in all groups showed a significant difference. There was a trend of increasing the ratio between IL-17 levels and IL-10 in all groups and the highest increase occurred in the control group which was 420%.

CONCLUSION: The higher the dose of BSGA extract administration could reduce the ratio between IL-17 levels and IL-10 and there is a correlation with a negative linear pattern between IL-10 and IL-17 with p = 0.034 which means that higher levels of IL-10 will reduce IL-17 levels.

Item Type:	Artikel Umum
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisi / Prodi:	Faculty of Pharmacy (Fakultas Farmasi) > S2-Master of Pharmacy (S2-Farmasi)
Depositing User:	Lalu Muhammad Irham, M.Farm., Ph.D
Date Deposited:	09 Jun 2022 01:46
Last Modified:	02 Nov 2022 07:13
URI:	http://eprints.uad.ac.id/id/eprint/35193

Actions (login required)

View Item