When plasma jet is effective for chronic wound bacteria inactivation, is it also effective for wound healing?

Darmawati, Sri and Rohmani, Afiana and Nurani, Laela Hayu and Evy Prastiyanto, Muhammad and Dewi, Sri Sinto and Salsabila, Nia and Wahyuningtyas, Eka Sakti and Murdiyae, Fri and Sikumbang, Isabella Meliawati and Nur Rohmah, Ratnasari and Fatimah, Yun Arifatul and Widiyanto, Andi and Ishijima, Tatsuo and Sugama, Junko and Nakatani, Toshio and Nasruddin, N (2019) When plasma jet is effective for chronic wound bacteria inactivation, is it also effective for wound healing? Clinical Plasma Medicine, 14. pp. 1-9.

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Abstract

Purpose: This investigation aimed to compare the effectiveness of two styles of plasma jet treatment (i.e., contact
and non-contact styles) for two biological materials, namely, wound related bacteria and acute wounds.
Method: An atmospheric plasma jet operated at a frequency of 18.32 kHz and high AC voltage with a peak-topeak voltage of 9.58 kV and a current of 55.2 mA was applied. Argon gas was used as the carries gas of plasma jet
generation and was fixed at a flow rate of 1 standard liters per minute (slm).Two biological materials (i.e.,
wound related bacteria and acute wound) were applied as experimental objects. The sample groups were based
on the two styles of plasma jet treatment: contact and non-contact styles. Microbial inhibition zone calculation
and macroscopic and histological observations were also performed.
Results: This investigation emphasized that the contact and non-contact styles of plasma jet treatment had
significantly different effects for wounds and wound-related chronic bacteria. On the one hand, the contact style
was visually attractive and more effective for inactivate bacteria. On the other hand, it caused negative effects,
such as damaging normal tissue, significantly impeding wound healing and impeding the growing of new epithelial tissue. The non-contact style, however, was less effective at inactivating bacteria; however, it could
accelerate wound healing.
Conclusion: In the context of wound healing, the non-contact style of plasma jet treatment may be better than the
contact style of plasma jet treatment.

Item Type:	Artikel Umum
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisi / Prodi:	Faculty of Pharmacy (Fakultas Farmasi) > S2-Master of Pharmacy (S2-Farmasi)
Depositing User:	Laela
Date Deposited:	14 Jul 2022 05:38
Last Modified:	14 Jul 2022 05:38
URI:	http://eprints.uad.ac.id/id/eprint/35828

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