Hasil cek similaritas JFSK 2022 : Inhibitory Activity of Parsea americana Mill. Peels Extract and Fraction Containing Phenolic Compound Against Staphylococcus aureus ATCC 25923

Sulistyani, Nanik (2022) Hasil cek similaritas JFSK 2022 : Inhibitory Activity of Parsea americana Mill. Peels Extract and Fraction Containing Phenolic Compound Against Staphylococcus aureus ATCC 25923. Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community), 19 (1). ISSN 1693-5683, e-ISSN 2527-7146

Text HASIL CEK_Sulistyani, Angelita, Nurkhasanah_inhibitory activity; Parsea americana Mill. peels; phenolic content; Staphylococcus aureus (4).pdf Download (2MB)

Abstract

Parsea americanaMill. is a natural resource that has been studied for its antibacterial properties.The pulp, peel, and seed of Parsea americanaMill. have potential as an antibacterial agent. This study aimed to determine the inhibitory activity and phenolic content of Parsea americanaMill. peels extract and fraction against Staphylococcus aureus ATCC 25923. Parsea americanaMill. was macerated with 96% ethanol and then fractionated with n-hexane, ethyl acetate, and methanol solvent. Determination of the fraction that has the greatest antibacterial activity against S. aureuswas carried out using the Kirby Bauer method. The total phenolic content in the extract and fraction was calculated as gallic acid equivalent (GAE) using the Folin-Ciocalteu method spectrometrically. Antibacterial activity test of the 96% ethanol extract, ethyl acetate fractions, and methanol fractions at a concentration of 10% w/v showed activity with a measurable inhibition zone. On the other hand, the n-hexane fraction showed no inhibition zone. The highest inhibition zone was the ethyl acetate fraction with approximately 8.33 ± 0.58 mm. The ethyl acetate fraction of ParseaamericanaMill. resulted in 536.26 ± 14.29 mg GAE/g fraction. The conclusion was that the ethyl acetate fraction had the highest total phenolic content and was the most active fraction in inhibiting the growth of Staphylococcus aureus.

Item Type:	Artikel Umum
Subjects:	A General Works > AC Collections. Series. Collected works
Divisi / Prodi:	Faculty of Pharmacy (Fakultas Farmasi) > Pharmacy Doc
Depositing User:	Dr Nanik Sulistyani
Date Deposited:	14 Nov 2022 03:10
Last Modified:	14 Nov 2022 03:10
URI:	http://eprints.uad.ac.id/id/eprint/37504

Actions (login required)

View Item