Comparison effectiveness of use antihypertensive in preeclampsia patient in RSUD Panembahan Senopati Bantul

Sari, Andriana and Pertiwi, Wisi Unggul and Baroroh, Faridah (2023) Comparison effectiveness of use antihypertensive in preeclampsia patient in RSUD Panembahan Senopati Bantul. Pharmaciana, 13 (2). pp. 197-203. ISSN ISSN:2088-4559,e-ISSN:2477-0256

Text 6. Andrianasari_197-203.pdf Download (233kB)

Abstract

Preeclampsia is one of many unsolved obstetric problems. The purpose of this research is to
compare effectiveness of antihypertensive in preeclampsia patient in RSUD Panembahan Senopati
Bantul in the period January-July 2019. This study needs to analyze about antihypertensive drugs in
preeclampsia because Preeclampsia is the 3rd rank of disease in pregnancy that causes maternal death
after hemorrhagic and cardiovascular diseases. The study was conducted at Panembahan Senopati
Hospital Bantul because hypertension in inpatient was ranked first in 10 distributions of noncommunicable
diseases. The research was observational analytic using a cross sectional study with
retrospective data collection of patient medical record. Samples were selected on inclusion and
exclusion criteria in 46 cases. Data analysis using Mann-Whitney to determine differences in drug
effectiveness and Fisher's to determine the relationship. The results are found that no relationship
between maternal age, obstetrical age, pregnancy status, method of birth, and length of stay, but there
was a relationship between the severity of preeclampsia with the achievement of blood pressure
targets. The results of comparative analysis of the effectiveness nifedipine monotherapy with
combination of nifedipine + methyldopa there was a significant difference (p = 0.006), and there was a
significant relationship between nifedipine monotherapy and combination of nifedipine + methyldopa
(p = 0.015) OR results = 7.200. The conclusion of this study is more effective to use the combination
of nifedipine + methyldopa for patients with preeclampsia.

Item Type:	Artikel Umum
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisi / Prodi:	Faculty of Pharmacy (Fakultas Farmasi) > S1-Pharmacy (S1-Farmasi)
Depositing User:	jurnal pharmaciana
Date Deposited:	19 Aug 2023 03:49
Last Modified:	19 Aug 2023 03:49
URI:	http://eprints.uad.ac.id/id/eprint/46428

Actions (login required)

View Item