Relationship between Appropriate Antibiotics Used Based on 2019 ATS/IDSA Guideline and Clinical Improvement in Inpatient Community-Acquired Pneumonia Patients

Maju, Mensiana Ayu and Setiawan, Christianus Heru (2023) Relationship between Appropriate Antibiotics Used Based on 2019 ATS/IDSA Guideline and Clinical Improvement in Inpatient Community-Acquired Pneumonia Patients. Media Farmasi, 20 (2). pp. 64-71. ISSN 1412-7946

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Abstract

Community-acquired pneumonia (CAP) can result from a bacterial infection that is acquired in the community. Without proper treatment, this infection can result in lung inflammation and death. An appropriate choice of empirical antibiotics can increase the success of therapy and prevent the development of bacterial resistance to various types of antibiotics. This study aims to assess the appropriateness of empiric antibiotic selection in CAP using the 2019 ATS/IDSA antibiotic guidelines and to analyze its relationship with the patient's clinical response. In this retrospective cohort study, we included patients aged >18 years with CAP who were hospitalized, received antibiotic therapy for pneumonia and had complete medical records. The medical record data, including antibiotics and clinical responses, were analyzed using the Mann-Whitney test. There was a difference in the average duration of clinical improvement (days), including body temperature, heart rate, and respiratory rate, in the group of pneumonia patients who used empiric antibiotics according to the guideline and those who did not follow it guidelines (p<.05). Empiric antibiotics based on the 2019 ATS/IDSA guidelines can improve therapy outcomes among inpatients with CAP. The results are expected to encourage doctors to select antibiotics following 2019 ATS/IDSA guidelines.

Item Type:	Artikel Umum
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisi / Prodi:	Faculty of Pharmacy (Fakultas Farmasi) > S1-Pharmacy (S1-Farmasi)
Depositing User:	mediafarmasi mediafarmasi
Date Deposited:	05 Sep 2023 06:39
Last Modified:	05 Sep 2023 06:39
URI:	http://eprints.uad.ac.id/id/eprint/50041

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